NEWS & CASES
  • Applications of Antifoam in Fermentation

    By : Zilibon Chemical
    2026/5/6
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    Industrial fermentation defoamers are composite agents formulated to meet food-grade standards. They are typically utilized for foam elimination and suppression across a wide range of fermentation processes, including microbial fermentation, fermentation extraction, dairy fermentation, yeast fermentation, alcohol fermentation, brewing, feed fermentation, bio-fermentation, bacterial fermentation, and edible mushroom fermentation.

    antifoam in fermentation

    The generation of foam during industrial fermentation is a normal phenomenon. The volume of foam is influenced by two primary factors: on one hand, it relates to the intensity of agitation and aeration; on the other, it depends on the specific properties of the culture medium. Protein-rich raw materials—such as peptone, corn steep liquor, soybean meal, and yeast extract—act as the primary foaming agents. Additionally, a high content of dextrin can also contribute to foam formation.

    Foaming patterns during fermentation typically manifest in the following ways:

    • Throughout the entire fermentation process, foam levels remain constant.
    • In the early stages of fermentation, foam levels initially rise but then decline steadily, subsequently remaining constant.
    • In the initial phase of fermentation, foam levels decrease slightly before beginning to rise again.
    • At the onset of fermentation, foaming potential is low but increases as the process continues.
    • A combination of the aforementioned patterns.

    The emergence of these specific patterns is contingent upon various factors, including the type of substrate used, the intensity of aeration and agitation, and the sterilization conditions. Among these factors, organic nitrogen sources within the substrate (such as soybean meal) are the primary contributors to foaming. Furthermore, the presence of abnormally high levels of foam can serve as an indicator of contamination by miscellaneous bacteria or bacteriophages.

    Consequently, while foam generation is an inherent part of the fermentation process, it requires timely and effective management. Industrial fermentation defoamers are specifically engineered to address the unique characteristics of fermentation processes. They can be added directly to the fermentation broth alongside the raw materials; the typical dosage ranges from approximately 0.01% to 0.05%, though the precise amount should be adjusted based on the actual foaming conditions observed on-site.

    Industrial fermentation defoamers are specialized agents refined through proprietary processes to ensure biological inertness. Compliant with food-grade standards, these defoamers can be introduced directly into the fermentation broth alongside the base raw materials—or added subsequently via continuous flow or supplementary feeding following high-temperature sterilization—to suit the specific requirements of the fermentation process. They offer distinct advantages, including exceptional stability during pre-fermentation high-temperature sterilization, effective foam suppression without inhibiting bacterial growth during fermentation, and the prevention of scale accumulation within the fermentation tank. Moreover, they facilitate easy separation from the final product and simplify the cleaning of the fermentation vessel after use.
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